In men Testosterone enanthate is applied during hrt during disorders related to testosterone deficiency: - delay of puberty; - hepatotoxicity, underdevelopment of the genital organs;-endocrine impotence; - hypopituitarism; - symptoms of male menopause (decreased libido, mental and physical activity); - посткастрационный androgen deficiency syndrome after castration); - osteoporosis is due to the development of the male hormone testosterone enanthate. to insufficiency androgénique.La testosterone is the primary male sex hormone synthesized and secreted by the testes. It stimulates the growth and development of male genital organs and secondary sexual characteristics (maturation of the prostate, seminal vesicles, penis and scrotum), the distribution of male hair on the face, pubis, chest), the development of the larynx, muscles of the body and the distribution of fats. Delays nitrogen, sodium, potassium and phosphorus, increases anabolism and reduces protein catabolism. A premature increase in the concentration of testosterone in the blood plasma before puberty causes the closure of the epiphyses and suspension of growth. Stimulates the production of erythropoietin and red blood cells. By the mechanism of negative feedback, it inhibits the secretion of luteinizing and follicle-stimulating hormones of the pituitary gland and inhibits spermatogenesis. In men with primary hypergonadotropic hypogonadism, there is a normalization of the level of gonadotropins.
In women, it inhibits the gonadotrophic function of the pituitary gland, the function of the ovaries, mammary glands, causes endometrial atrophy. Antagonistic effect in relation to estrogens is used in the treatment of fibroids, endometriosis, breast cancer. Shows a favorable effect in the complaints of the climacteric period.
The absorption of Testosterone Enanthate is relatively slow. Its greatest concentration in the blood occurs 72 hours after injection. The period of action lasts 2-4 weeks. When entering the human blood, 98% of the hormone binds to the fraction of globulins, which binds testosterone and estradiol.
Testosterone is processed by the liver, the body is mainly excreted by the kidneys, a small part is excreted with feces.
Testosterone enanthate is administered intramuscularly, deep into the gluteal muscle. The dosage regimen is selected individually, depending on the disease, gender, age, clinical effect.
- As a rule, adults are administered intramuscularly at 50-200 mg after 2-4 weeks.
- It is not recommended to exceed the dose of 400 mg per month. The duration of treatment is established individually.
- With hypogonadism in men as eunuchoidism, the recommended doses are 50-400 mg every 2-4 weeks.
- With the delay of puberty, 50-200 mg is used every 2-4 weeks 4-6 months.
- In breast cancer in women: 200-400 mg every 2-4 weeks.
The drug can not be administered intravenously
|Active substance:||Testosterone, Testosterone enantato|
|Active ingredient, mg:||250|
|1 bottle, ml:||1|
|Ampoules per package, pcs:||10|
|Manufacturer:||Euro Prime Farmaceuticals|