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Anastrozol 1 mg Balkan Pharmaceuticals

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Emory Montgomery
Edited By:
Emory Montgomery
Updated:
03/03/2021
Status:
Checked

The article is for informational purposes and is compiled according to the official instructions

Anastrozole

Anastrozole is an antitumor agent that inhibits the synthesis of estrogens. It inhibits the activity of aromatase, blocks the transformation of androstendon into estradiol. The drug has a positive effect in the treatment of estrogen-dependent tumors during postmenopause. Progestagenic, estrogenic and androgenic activity were not observed.

Anastrozole description

Powerful, highly selective non-steroidal flavor inhibitor. On women with breast cancer, has a therapeutic effect by reducing the level of estradiol. Women taking anastrozole in a dose of 1 mg, reduce the level of estradiol by 80%. When taken up to 10 mg per day does not affect the secretion of cortisol and aldosterone, ie, no need for the introduction of substitution corticosteroid therapy.

Anastrozole is used for:

  • Treatment of estrogen-dependent breast cancer in the postmenopause period;
  • Treatment of common breast cancer in the postmenopause period;
  • Adjuvant therapy of breast cancer in the period of postmenopause, in the early stages, after tamoxifen treatment for 2-3 years.

The active ingredient is anastrozole; one tablet contains 1 mg; auxiliary components: dye FD & C yellow #5, crosspovidone, magnesium stearate, povidone, lactose. By pharmacological group refers to hormone antagonists and similar means. Available in blisters of 20 tablets, one package contains 3 blisters. The tablets are flat, the color - yellow, square shape, on the surface of the tablets may be marbled.

The action of Anastrozole

Absorbed in a short period of time, when receiving on an empty stomach within two hours, the maximum concentration in the blood is reached. It is concluded rather slowly, the half-life is 40-50 hours. If applied on a full stomach, the absorption rate slows down. The dependence of pharmacokinetic parameters on the dosage or time of intake has not been studied. The effect of anastrozole does not depend on the age of women in postmenopause. The concentration of anastrozole in the blood reaches equilibrium approximately one week after the start of administration. In 72 hours after taking, 10% of the anastrozole is excreted in the urine and 60% is excreted as metabolites.

Course and dosages

When prescribing your own anastrozole dosage, you should be careful not to rely on past experience with the same testosterone ester and similar dosage. It is always possible that your aroma level will be different with each new course, because a mistake could be made by the manufacturer, the product could be counterfeit, the manufacturer could change, and your body could react differently each time. Whatever the case, you should periodically recheck the level of aromatization and adjust the dosage of anastrozole. As an exception, you can consider a course with trenbolone, because the real level of aromatization cannot be determined during this course, in which case, the dosage of anastrozole is adjusted according to the experience from the previous course, in which a similar dosage of testosterone and its ester was used.

For example, if you are taking steroids with a low half-life (methandrostenolone), start taking anastrozole at a lower dosage and frequency (0.5 mg three times a week or every other day), and after 10-15 days retest the estradiol and in case of deviations more/less, change the dosage frequency and dosage more/less respectively. After 15 to 20 days of use, we recommend repeating the blood test.

When using testosterone propionate, for example 100 mg \ every other day, the dosage of anastrozole may be 0.5 mg every other day, and every day 0.5 mg, as well as every day of 1 mg, and the last anastrozole intake should be on the fifth day after the last injection. 

Contraindications

  • Hypersensitivity to the components of the drug;
  • Treatment with tamoxifenom;
  • Lactation period;
  • Horse failure;
  • Expressed or moderate liver failure;
  • Pregnancy;
  • Age up to 18 years;
  • Treatment with estrogen-containing medications.

Side effects of taking Anastrozole

When using Anastrozol, such adverse reactions may occur:

  • Insomnia;
  • Bronchitis;
  • Anxiety;
  • Anemia;
  • Weight gain.
Nome del prodotto Prezzo
Anastrazolos 1 mg Pharmacom Labs 50 €
Anastrozol 1 mg Balkan Pharmaceuticals 25 €
Anastrozole 1 mg Teva 30 €

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Dominic Nelson

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